Created a diocese on 5 June 1991, during Pope John Paul II’s visit to Białystok. Erected on 25 March 1992 by Pope John Paul II by the bull Totus Tuus Poloniae populus. The capital of diocese is Drohiczyn with the Cathedral of the Holy Trinity. The patron saints of the diocese are the Blessed Virgin Mary, Mother of the Church, and St. Casimir, royal prince.